Characteristics of excluded studies [ordered by study ID]
| Study | Reason for exclusion |
|---|---|
| Ascaso 1992 | Study medication was not an IOP-lowering drop. |
| Bergamini 1997 | Non-comparative study. |
| Bucci 1987 | Study medications were not IOP-lowering drops. |
| Champagne 2015 | Study medications were not IOP-lowering drops. |
| Chen 2001 | Included participants who received laser peripheral iridotomy, ALT, and Nd:YAG laser capsulotomy; results not separated by type of surgery |
| Chen 2005 | Included participants who received laser peripheral iridotomy, ALT, and Nd:YAG laser capsulotomy; results not separated by type of surgery |
| De Keyser 2017 | Study medication was not an IOP-lowering drop. |
| Diestelhorst 1995 | Study medication was not an IOP-lowering drop. |
| Gelfand 1985 | Study medication was not an IOP-lowering drop. |
| Herbort 1992 | Study medication was not an IOP-lowering drop. |
| Herbort 1993 | Study medication was not an IOP-lowering drop. |
| Hurvitz 1994 | Dosage study; no eligible comparison group. |
| Jinapriya 2014 | Study medication was not an IOP-lowering drop. |
| Kim 1998 | Study medication was not an IOP-lowering drop. |
| Krupin 1992 | Not an RCT. |
| Leung 1986 | Not an RCT. |
| León-Alcántara 1995 | Non-comparative study. |
| Ottaiano 1989 | Included only participants who received laser iridotomy. |
| Ottaiano 1996 | Unable to confirm whether study was randomized. |
| Pappas 21985 | Study medication was not an IOP-lowering drop. |
| Patel 1998 | Unable to confirm whether study was randomized; included participants who received ALT or Nd:YAG capsulotomy; results not separated by type of surgery |
| Realini 2010 | Study medication was not an IOP-lowering drop. |
| Rosenberg 1995 | Dosage study; no eligible comparison group. |
| Shin 1996 | Study medication was not an IOP-lowering drop. |
| Stingu 2001 | Unable to confirm whether study was randomized; included participants who received ALT, and Nd:YAG laser iridotomy; results not separated by type of surgery |
| Swendris 1991a | Unable to confirm whether study was randomized; categorized by handsearchers as a CCT as no randomization was reported |
| Swendris 1991b | Unable to confirm whether study was randomized; categorized by handsearchers as a CCT as no randomization was reported |
| Threlkeld 1996 | Dosage study; no eligible comparison group. |
| Vickerstaff 2015 | 1 study arm received only medication without LTP; no eligible comparison group |
| Weinreb 1983 | Study medication was not an IOP-lowering drop. |
| West 1992 | Study medications were not IOP-lowering drops. |
ALT: argon laser trabeculoplasty; CCT: controlled clinical trial; IOP: intraocular pressure; LTP: laser trabeculoplasty; Nd:YAG: neodymium-doped yttrium aluminum garnet; RCT: randomized controlled trial.