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. Author manuscript; available in PMC: 2017 Oct 20.
Published in final edited form as: JACC Basic Transl Sci. 2017 Apr 24;2(2):160–180. doi: 10.1016/j.jacbts.2016.12.002

Figure 11. PP2Ce expression promotes myocytes death and perturbs pro-survival signaling following oxidative injury.

Figure 11

Figure 11

A. NRVMr viability measured by MTT assay in NRVM expressing GFP or PP2Ce following H2O2 treatment for 16 hours at different doses as indicated. Replicate number is labeled in each corresponding columns. **: p<0.01 vs. untreated. ##: p<0.01 between GFP and PP2Ce groups at same doses. B. NRVM viability expressing GFP (n= 8) or PP2Ce (n=8) under untreated or following 24 hours of treatment of 2μM ionomycin. **: p<0.01 vs. untreated. ##: p<0.01 between GFP and PP2Ce groups. C. Immunoblot analysis of intracellular signaling molecules as indicated in NRVM expressing GFP or PP2Ce with 50μM H2O2 treatment at different time points as indicated. tunicamycin (5μg/ml for 4 hours) was used as a control. D. Quantification of signaling molecules as indicated with independent experimental replicate number labeled in each column.