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. Author manuscript; available in PMC: 2017 Oct 20.
Published in final edited form as: JACC Basic Transl Sci. 2017 Apr 24;2(2):160–180. doi: 10.1016/j.jacbts.2016.12.002

Figure 5. ISO mediated regulation of PP2Ce protein in cardiomyocytes.

Figure 5

A. PP2Ce and PP2Cα expression in NRVM following ISO treatment. B. PP2Ce expression in NRVM treated with ISO (1μM) with or without co-treatment of proteasome inhibitor MG132 (10μM) or lysosomal inhibitor BAF (50nM) as indicated. C. Quantification of PP2Ce expression in NRVM treated with ISO with or without additional treatment of cycloheximide (CHX), MG132 or BAF as indicated. n: number of total experimental replicates, *: p< 0.05, **: p<0.01. D. PP2Ce expression in NRVM treated ISO or forskolin (FSK) at 0.1, 1, and 10μM concentrations as indicated. E. PP2Ce expression in NRVM treated with FSK (1μM) with or without PKA inhibitor H89 (1μM) as indicated.