Figure 8. PP2Ce expression impairs ISO stimulated enhancement of contractility.
A. Representative left ventricle pressure (LVP) measured from isolated hearts of wildtype or PP2Ce TG mice at basal or perfused by 1μM of ISO. B. Hemodynamic parameters from control (n= 9) and PP2Ce TG (n=6) hearts at basal or treated by 10nM ISO. Pmax: maximal pressure, Pmin: minimal pressure, dP/dT: maximal or minimal pressure derivatives, LVDP: left ventricle developed pressure, Tau: relaxation index. *: p<0.05, **: p < 0.01 between basal and I/R within control or PP2Ce TG groups. #: p < 0.05 between corresponding control and PP2Ce TG.