. Author manuscript; available in PMC: 2017 Oct 20.

Published in final edited form as: JACC Basic Transl Sci. 2017 Apr 24;2(2):160–180. doi: 10.1016/j.jacbts.2016.12.002

Table 2.

Hemodynamic parameters. Cardiac performance was measured from isolated non- transgenic (Control, n=9) and the PP2Ce transgenic (TG, n=6) hearts under basal (Basal) and post 30 mins global ischemia and 45 mins reperfusion (I/R).

	Control (n=9)		TG (n=6)
	Basal	I/R	Basal	I/R
HR (bpm)	403.5±96.4	334.7±87.2	390.0±74.6	281.8±49.9

Pmax (mmHg)	91.22±20.67	95.50±10.60	98.55±17.72	94.35±10.42

Pmin (mmHg)	3.68±2.30	39.71±12.52^##	4.28±2.44	55.03±11.26^*^##

dP/dt max (mmHg/sec)	4794.9±446.4	2906.0±490.8^##	4942.2±871.5	1839.8±411.0^**^##

dP/dt min (mmHg/sec)	3031.6±359.8	1867.3±235.3^##	3156.9±435.6	1225.6±344.6^**^##

LVDP (mmHg)	87.54±18.76	55.79±8.31^##	94.27±18.45	39.33±11.64 ^##

Values are means ± SEM. HR: heart rate, Pmax: systolic pressure, Pmin: diastolic pressure, dP/dt max: maximal systolic pressure derivative, dP/dt min: maximal diastolic pressure derivative, LVDP: left ventricle developed pressure (Pmax-Pmin).

p< 0.05,

^**

p< 0.01 between corresponding Control and TG groups.

^##

p<0.01 between basal and I/R within Control or TG groups.