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. Author manuscript; available in PMC: 2017 Jun 2.
Published in final edited form as: J Vis Exp. 2016 Nov 8;(117):10.3791/54720. doi: 10.3791/54720

Figure 3. Ag-specific iPSC-Tregs Infiltrate into the Knee Joints.

Figure 3

Ag-specific iPSC-Tregs were adoptively transferred into C57BL/6 mice. Shortly after arthritis induction (days 7 - 14), the knees were removed and stained for immunohistology (scale bars: 20 μm). Mice receiving OVA-specific iPSC-Tregs have large numbers of TCRVβ5+ cells in the knees.