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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Pharm Biol. 2017 Dec;55(1):481–486. doi: 10.1080/13880209.2016.1251468

Figure 2.

Figure 2

Protective effects of MESA on the DA neurodegeneration in C. elegans. GFP expression patterns of MPP+-treated transgenic strain BZ555 (Pdat-1::GFP) (A) and UA57 (Pdat-1::GFP and Pdat-1::CAT-2) (B). The fluorescence signals of DA neuron were photographed at 200 × magnification using fluorescence microscope. All eight DA neurons were counted in each survived animal by inspecting the GFP fluorescence of BZ555 (C) and UA57 (D), respectively. Data are expressed as the mean ± S.E.M. and results are obtained from three independent assays. Significance of difference between MESA treatment and control was determined by a one-way ANOVA. ###p <0.001 compared with vehicle alone, *p <0.05 and ***p <0.001 compared with control.