Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
(A) Crystal structures of 14 (orange) and 15 (yellow) bound to CARM1 are superimposed (PDB ID: 2Y1W and 2Y1X). Key interactions of 14 in arginine binding channel are indicated. (B) Crystal structures of MS023 (gray) and 16 (blue) bound to PRMT6 are superimposed (PDB ID: 5E8R and 5EGS), and key interactions for 16 are shown. Hydrogen bonds are represented as magenta dashed lines and water molecule as red sphere.
