. Author manuscript; available in PMC: 2018 Aug 1.

Published in final edited form as: Cold Spring Harb Perspect Biol. 2017 Aug 1;9(8):a023499. doi: 10.1101/cshperspect.a023499

Table 2.

Incubation periods of the Fukuoka-1 (FU-1) prion strain in transgenic mice.

Inoculum	Host	Incubation period (days) ^a	n/n₀ ^b
RML brain homogenate	Tg(MoPrP)4053	51 ± 3 ^c	8/8
RML brain homogenate	Tg(Mo/HuPrP)1014/Prnp^0/0	107 ± 5 ^c	4/4
CJD brain homogenate	Tg(Mo/HuPrP)1014/Prnp^0/0	78 ± 1 ^c	7/7
CJD brain homogenate	Tg(HuPrP)2669/Prnp^0/0	143 ± 2 ^c	9/9
RML/N2a cell lysate	Tg(MoPrP)4053	77 ± 3	8/8
RML/N2a cell lysate	Tg(Mo/HuPrP)1014/Prnp^0/0	154 ±1	8/8
FU-1/N2a cell lysate	Tg(MoPrP)4053	103 ± 2	8/8
	Tg(Mo/HuPrP)1014/Prnp^0/0	103 ± 4	8/8
	Tg(HuPrP)2669/Prnp^0/0	> 500	0/8
FU-1/N2a cell lysate -> Tg(MoPrP)4053	Tg(MoPrP)4053	76 ± 0	8/8
	Tg(Mo/HuPrP)1014/Prnp^0/0	82 ± 2	7/7
	Tg(HuPrP)2669/Prnp^0/0	> 500	0/6
FU-1/N2a cell lysate -> Tg(Mo/HuPrP)1014	Tg(MoPrP)4053	120 ± 10	8/8
	Tg(Mo/HuPrP)1014/Prnp^0/0	95 ± 2	8/8
	Tg(HuPrP)2669/Prnp^0/0	> 500	0/6

Data reported as mean ± standard error of the mean

n, number of mice showing clinical signs of disease; n₀, number of mice inoculated

Data previously reported in (Berry et al. 2013)