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Both TTX and LS depressed the amplitude of recurrent monosynaptic connections between layer 2/3 pyramidal neurons. A. Examples of evoked recurrent EPSCs in response to the firing of presynaptic neurons at 20 Hz in control, LS, and TTX conditions. B. Average EPSC amplitude (pA), paired pulse ratio (PP ratio), coefficient of variation (CV) and failure rates (% failures) for control (black), (white) and TTX (gray) conditions. * = significantly different from control.
