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. Author manuscript; available in PMC: 2017 Aug 15.
Published in final edited form as: Cold Spring Harb Perspect Med. 2016 Oct 3;6(10):a026831. doi: 10.1101/cshperspect.a026831

Figure 1.

Figure 1

A simplistic illustration of the diverse functions of HDACs and HDACi regulating different stages of cancer through multiple different mechanisms and changing different biological processes. Far right, ↑ indicates promotion or upregulation, ↓ indicates repression or downregulation.