Table 2.
Columbia | Harvard | Michigan | UTSW | Statistic | ||||||
---|---|---|---|---|---|---|---|---|---|---|
MDD+ | MDD− | MDD+ | MDD− | MDD+ | MDD− | MDD+ | MDD− | |||
n | n | n | n | n | n | n | n | |||
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Group | 44 | 12 | 34 | 17 | 33 | 9 | 59 | 14 | χsite(3) = 3.74, p = 0.29 | |
Course | χsite(3) = 6.18, p = 0.10 | |||||||||
Recurrent | 36 | -- | 26 | -- | 32 | -- | 51 | -- | ||
Single Episode | 8 | -- | 8 | -- | 1 | -- | 8 | -- | ||
Gender | χsite(3) = 2.59, p = 0.47 | |||||||||
M | 21 | 4 | 16 | 8 | 11 | 3 | 20 | 8 | ||
F | 23 | 8 | 18 | 9 | 22 | 6 | 39 | 6 | ||
Education Level | χsite(3) = 5.78, p = 0.12 | |||||||||
≥16 years | 26 | 7 | 15 | 9 | 14 | 5 | 21 | 8 | ||
< 16 years | 16 | 5 | 19 | 8 | 19 | 4 | 38 | 6 | ||
Lifetime Psychopathology | ||||||||||
Panic Disorder | 9 | 0 | 6 | 0 | 5 | 0 | 7 | 0 | χsite(3) = 1.40, p = 0.71 | |
OCD | 0 | 0 | 2 | 0 | 0 | 0 | 4 | 0 | χsite(3) = 5.20, p = 0.16 | |
Specific Phobia | 8 | 0 | 6 | 0 | 11 | 0 | 7 | 0 | χsite(3) = 6.46, p = 0.09 | |
Social Phobia | 2 | 0 | 0 | 0 | 4 | 0 | 9 | 0 | χsite(3) = 4.99, p = 0.17 | |
PTSD | 6 | 0 | 1 | 0 | 11 | 0 | 9 | 0 | χsite(3) = 11.97, p = 0.01 | |
Anorexia | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | χsite(3) = 1.39, p = 0.71 | |
Bulimia | 0 | 1 | 3 | 0 | 0 | 0 | 1 | 0 | χsite(3) = 5.51, p = 0.14 | |
Alcohol Use Disorder | 6 | 0 | 2 | 1 | 10 | 0 | 15 | 0 | χsite(3) = 8.78, p = 0.03 | |
Illicit Use Disorder | 5 | 1 | 3 | 0 | 6 | 0 | 12 | 0 | χsite(3) = 3.00, p = 0.39 | |
Mean (SD) Range |
Mean (SD) Range |
Mean (SD) Range |
Mean (SD) Range |
Mean (SD) Range |
Mean (SD) Range |
Mean (SD) Range |
Mean (SD) Range |
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Number of Episodes^& | 5.32 (6.23) 1−20 |
-- | 6.18 (6.31) 1–20 |
-- | 9.36 (6.74) 1–20 |
-- | 9.14 (7.60) 1–20 |
-- | Fsite(3,166) = 2.85, p = 0.04, Post Hoc: M > C, M > H | |
Age | 34.45 (10.52) 18–61 |
36.92 (13.23) 18–64 |
35.44 (14.69) 18–60 |
39.24 (18.46) 18–65 |
34.36 (13.11) 18–58 |
43.78 (15.19) 23–62 |
41.37 (11.40) 19–63 |
32.71 (11.75) 20–57 |
Fsite(3,214) = 0.37, p = 0.77, FDX(1,214) = 0.69, p = 0.41, Fint(3,214) = 3.30, p = 0.02 | |
Total Brain Volume* | 1.15 (0.14) 0.85–1.54 |
1.14 (0.13) 0.99–1.44) |
1.12 (0.10) 0.91–1.41 |
1.12 (0.11) 0.87–1.29 |
1.12 (0.12) 0.92–1.43 |
1.09 (0.15) 0.90–1.28 |
1.11 (0.11) 0.85–1.39 |
1.19 (0.16) 0.97–1.54 |
Fsite (3,214) = 1.23, p = 0.30, FDX(1,214) = 0.24, p = 0.62, Fint(3,214) = 1.82, p = 0.14 | |
Quick Inventory of Depression Symptoms | 19.00 (2.98) 14–24 |
1.50 (1.13) 0–4 |
17.65 (2.89) 14–27 |
1.12 (1.05) 0–3 |
18.67 (3.27) 14–27 |
2.22 (1.99) 0–6 |
17.28 (2.43) 14–24 |
1.14 (1.29) 0–4 |
Fsite(3, 213) = 2.11, p = 0.10, FDX(1,213) = 1,561, p < 0.01, Fint(3,213) = 0.51, p = 0.68 |
Note:
For ANOVA, data was log10 +1 transformed due to positive skew;
Data was windsored to 20 for reporting descriptive statistics.
105 and millimeters3 2 participants at Columbia declined to report education.