Figure 4.
Summary of forebrain and brainstem seizure thresholds in C57BL/6J and DBA/2J mice exposed to the repeated-flurothyl model. One-way analysis of variance (ANOVA) followed by Tukey HSD post-hoc comparisons were used to determine significance between day one, day eight and flurothyl rechallenge (eight flurothyl induction trials plus a 28-day incubation) within and between strains (C57BL/6J and DBA/2J mice). * Significantly different comparing forebrain seizure threshold (FBT) and brainstem seizure threshold (BST) within strain (p < 0.0002), ** significantly different comparing BST within strain (p < 0.004), + significantly different comparing FBT between strains (p < 0.0002), ++ significantly different comparing BST between strains (p < 0.0002).