Table 2.
Iron content (μg Fe/g of tissue) of each region in bvFTD, PPA and control group
| Region | Controls | bvFTD | PPA | Bonferroni corrected P value | ||
|---|---|---|---|---|---|---|
| bvFTD vs Controls | PPA vs Controls | bvFTD vs PPA | ||||
| LSFG | 13.17±5.78 | 24.35±10.02 | 18.61±4.23 | <0.001 | 0.123 | 0.09 |
| RSFG | 12.55±5.51 | 25.36±9.82 | 18.45±5.11 | <0.001 | 0.75 | 0.03 |
| LPCG | 35.16±10.03 | 40.17±7.39 | 37.14±8.28 | 0.064 | 1.00 | 0.914 |
| RPCG | 33.46±14.29 | 41.74±7.1 | 39.2±12.11 | 0.012 | 0.416 | 1.00 |
| LAC | 17.21±7.71 | 21.31±5.72 | 18.57±4.21 | 0.034 | 1.00 | 0.634 |
| RAC | 16.72±5.7 | 22.15±6.1 | 17.97±3.79 | 0.001 | 1.00 | 0.092 |
| LIN | 12.44±5.4 | 15.91±7.09 | 15.33±5.33 | 0.074 | 0.512 | 1.00 |
| RIN | 11.86±5.59 | 16.55±7.83 | 14.14±2.78 | 0.01 | 0.883 | 0.793 |
| LCAU | 25.76±12.05 | 29.00±12.46 | 27.19±4.88 | 0.756 | 1.00 | 1.00 |
| RCAU | 24.96±13.46 | 31.43±13.79 | 25.87±7.32 | 0.13 | 1.00 | 0.609 |
| LPUT | 20.96±11.23 | 26.98±8.95 | 21.18±5.33 | 0.037 | 1.00 | 0.227 |
| RPUT | 20.61±9.5 | 27.84±8.12 | 21.13±6.49 | 0.003 | 0.06 | 0.066 |
| LGP | 27.58±10.25 | 30.66±9.08 | 28.39±7.58 | 0.55 | 1.00 | 1.00 |
| RGP | 26.65±7.27 | 32.3±11.51 | 28.11±8.68 | 0.053 | 1.00 | 0.585 |
| LFWM | 13.96±6.61 | 14.67±5.91 | 15.21±3.17 | 1.00 | 1.00 | 1.00 |
| RFWM | 13.65±5.98 | 17.08±6.77 | 13.30±4.64 | 0.078 | 1.00 | 0.217 |
| LHP | 12.28±7.60 | 15.64±7.07 | 15.58±4.09 | 0.156 | 0.493 | 1.000 |
| RHP | 11.95±6.6 | 17.01±8.82 | 14.89±4.21 | 0.024 | 0.671 | 1.00 |
| LTP | 13.72±5.44 | 21.90±8.69 | 19.67±5.16 | <0.001 | 0.041 | 1.00 |
| RTP | 13.25±5.9 | 23.41±8.71 | 18.77±4.35 | <0.001 | 0.07 | 0.166 |
| LRN | 27.29±11.07 | 30.39±10.99 | 27.90±7.99 | 0.709 | 1.00 | 1.00 |
| RRN | 24.21±9.13 | 31.58±12.66 | 24.69±9.05 | 0.02 | 1.00 | 0.177 |
| LSN | 26.78±11.63 | 30.90±9.90 | 28.05±10.64 | 0.365 | 1.00 | 1.00 |
| RSN | 26.64±12.49 | 31.0±11.25 | 27.85±11.09 | 0.403 | 1.00 | 1.00 |
| LDN | 20.71±8.84 | 23.26±7.86 | 21.41±7.47 | 0.633 | 1.00 | 1.00 |
| RDN | 19.93±6.5 | 24.03±8.41 | 20.47±3.96 | 0.064 | 1.00 | 0.424 |
Bonferroni posthoc tests compare differences between groups
R-right, L-left, bvFTD –frontal variant frontotemporal Dementia, PPA- primary progressive aphasia
SFG- superior frontal gyrus, PCG- precentral gyrus just anterior to central sulcus, AC- grey matter abutting and posterior to the cingulate sulcus along with adjacent medial frontal lobe, IN-insula, CAU-caudate, PUT-putamen, GP-globus pallidus, FWM-frontal white matter, HP-head and body of hippocampus, TP-temporal pole, RN-red nucleus, SN-substantia nigra, DN-dentate nucleus.