Table 1. Cox proportional hazard model of imaging, molecular, clinical, and demographic biomarkers.

	Univariate analysis			Multivariate analysis I			Multivariate analysis II
Variables	B	HR	P-value	B	HR	P-value	B	HR	P-value
Vol-CE	0.63	1.89	0.499
Vol-FLAIR	0.47	1.60	0.415				0.69	2.01	0.577
CBV-SE	−1.77	0.17	0.171
CBV-GE	−1.17	0.31	0.133
CBF-SE	−1.08	0.34	0.267
CBF-GE (rCBF)	−0.98	0.38	0.108
tCho/NAA	1.57	4.83	0.158
tCho/hCre	4.45	85.85	0.006
MGMT	−2.21	0.11	0.008	−1.79	0.17	0.049	−1.34	0.26	0.216
Age	−0.07	0.93	0.015	−0.05	0.96	0.131	−0.03	0.97	0.365
KPS	−3.93	0.02	0.032	0.11	1.11	0.958
tCho/hCr+rCBF	0.39	1.47	0.001	0.59	1.79	0.019
					0.72	2.04	0.001	0.65	1.91	0.035
					0.76	2.14	0.002

P-values less than 0.05 are shown in bold