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. Author manuscript; available in PMC: 2018 Sep 12.
Published in final edited form as: Mult Scler. 2017 Aug 2;24(10):1288–1300. doi: 10.1177/1352458517721356

Figure 2. MS risk factors, genetic variation in the VMP1 gene and smoking, do not affect DNA methylation in the VMP1/MIR21 locus.

Figure 2

DNA methylation levels (β-values) in the VMP1/MIR21 locus, exemplified by cg07181702, do not associate with the MS risk genotype at RS8070345 (T=risk allele) in a large cohort of healthy individuals (A) or in the Swedish cohort (B). Detailed analysis of the locus is given in Table 2 and Table 3. (C) DNA methylation levels (β-values) in the VMP1/MIR21 locus, exemplified by cg07181702, are not affected by the smoking status in a large cohort of healthy individuals. Detailed analysis of the locus is given in Table 2.