Table III.

Brain activation in mothers with addictions to the contrast of own happy (OH) versus unknown happy (UH)

	Hemisphere	Talairach coordinates a			Peak t value	p	Volume b (mm3)
		x	y	z
Frontal lobe
Superior Frontal Gyrus	Right	2	−5	60	7.99	< .00000001	507
Precentral Gyrus	Right	41	−2	27	7.21	.00000002	357
Precentral Gyrus/Postcentral Gyrus	Left	−43	−17	45	6.19	.00000043	469
Parietal lobe
Precentral Gyrus/Postcentral Gyrus	Right	50	−17	42	9.24	< .00000001	1853
Superior Parietal Lobule	Right	23	−59	30	6.14	.00000051	360
Temporal/Occipital lobe
Fusiform Gyrus/Inferior Temporal  Gyrus/Occipital Gyri	Left	−28	−47	−18	9.37	< .00000001	8044
Occipital Gyri	Right	29	−77	0	7.51	.00000001	2275
Fusiform Gyrus	Right	32	−44	−15	7.40	.00000001	2631
Sub-lobar regions
Middle Cingulate Gyrus	Right/Left	−1	−5	33	10.10	< .00000001	1395
Limbic c							2869
Dorsal Putamen/Globus Pallidus	Left	−22	−2	−6	8.77	< .00000001
Parahippocampal Gyrus	Left	−28	−5	−30	6.59	.00000013
Insula/Inferior Frontal Gyrus	Left	−40	4	12	8.04	< .00000001	946
Parahippocampal Gyrus/Lateral Amygdala	Right	23	−5	−27	8.02	< .00000001	1531
Midbrain/limbic c							8895
Thalamus	Left	−7	−23	6	7.98	< .00000001
Substantia Nigra	Right	4	−26	−9	7.26	.00000002
Thalamus	Right	2	−14	8	7.01	.00000004
Ventral Tegmental Area	Right/Left	−1	−16	−9	6.90	.00000005
Hippocampus	Right	23	−23	−6	6.75	.00000008
Substantia Nigra	Left	−4	−17	−9	6.48	.00000018
Globus Pallidus	Right	17	−5	−6	6.59	.00000013	324
Posterior Cingulate Gyrus	Left	−4	−53	9	6.36	.00000026	720
Cerebellum
Anterior Lobe, Culmen	Right	29	−50	−21	9.38	< .00000001	4395
Anterior Lobe, Cerebellar Lingual	Left	−4	−44	−9	7.76	< .00000001	345
Anterior Lobe, Culmen	Right	14	−59	−18	6.25	.00000036	602
Posterior Lobe, Cerebellar Tonsil	Left	−7	−50	−30	6.21	.00000041	494

Note. Data shown are from the activation map for the OH > UH contrast, thresholded at FDR-corrected q < .001 and a minimum cluster size of 300 mm³. Results are presented at a more stringent threshold of q < .001 to better delineate specific neuroanatomical locations of activated clusters. Within each lobe, clusters are ordered by decreasing level of significance.

^aTalairach coordinates in millimeters with origin at the anterior commissure, representing peak voxels in each cluster. x, y, z coordinates refer to right (+) to left (−), anterior (+) to posterior(−), and superior (+) to inferior(−), respectively.

^bNumber of contiguously activated voxels within a cluster.

^cNote that where no volume is given for an anatomical region, it forms part of a larger cluster that spans anatomically distinct regions.