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. Author manuscript; available in PMC: 2017 Aug 23.
Published in final edited form as: J Vis Exp. 2016 Nov 24;(117):10.3791/54814. doi: 10.3791/54814

Figure 5. Typical ECG Changes Over the Course of an Ischemia/Reperfusion Surgery.

Figure 5

This figure follows one mouse over the duration of myocardial Ischemia/Reperfusion surgery. The first waveform displays a normal sinus rhythm which was the recorded baseline (Baseline). The second waveform (1 min ischemia) displays the waveform 1 min after the ligature was tied and the artery became occluded. The red circle on this line shows hyperacute T-wave peaking. The red circle on the third waveform (5 min Ischemia) displays the complete ST-segment elevation. The red circle on the fourth waveform (20 min Ischemia) displays a widened QT-interval and the S-wave is still elevated. The red circle on the fifth waveform (45 min Ischemia) displays widened QT-segment and elevated ST-segment. The sixth waveform (1 min Reperfusion) displays no significant changes versus 45 min ischemia. The red circle on the seventh waveform (5 min Reperfusion) displays deep, significant Q-wave form. The first red circle in the eighth waveform (30 min Reperfusion) displays significant Q-waves, while the second red circle displays possible T-wave enhancement. Please click here to view a larger version of this figure.