Table 1.
Baseline characteristics of participants stratified by plasma galectin-3 quintiles, ARIC, 1996 – 1998
| Characteristics* | Galectin-3 Quintiles (ng/mL)
|
p-trend | ||||
|---|---|---|---|---|---|---|
| Q1 (4.4 – 11.4) |
Q2 (11.5 – 13.3) |
Q3 (13.4 – 15.1) |
Q4 (15.2 – 17.5) |
Q5 (17.6 – 114.0) |
||
| N | 1973 | 2052 | 1951 | 1954 | 1986 | – |
| Age (years) | 61.4 (5.4) | 62.1 (5.6) | 62.6 (5.6) | 63.1 (5.6) | 64.4 (5.7) | <0.0001 |
| Sex (% female) | 38.7 | 49.0 | 56.5 | 64.5 | 72.7 | <0.0001 |
| Race (% black) | 16.3 | 19.2 | 21.2 | 24.4 | 28.2 | <0.0001 |
| Diabetes | 13.9 | 13.7 | 15.7 | 17.0 | 21.8 | <0.0001 |
| BMI (kg/m2) | 27.9 (4.6) | 28.1 (5.1) | 28.5 (5.3) | 29.1 (5.7) | 29.9 (6.4) | <0.0001 |
| eGFR (ml/min per 1.73 m2) | 91 (13) | 89 (14) | 88 (14) | 86 (15) | 79 (21) | <0.0001 |
| CRP (mg/L)† | 1.6 (0.8 – 3.5) |
1.9 (0.9 – 4.5) |
2.3 (1.1 – 5.1) |
3.0 (1.3 – 6.1) |
4.0 (1.6 – 8.0) |
<0.0001 |
| Troponin T (ng/L)† | 5.0 (3.0 – 7.0) |
5.0 (3.0 – 8.0) |
5.0 (3.0 – 8.0) |
4.0 (3.0 – 8.0) |
6.0 (3.0 – 10.0) |
<0.0001 |
| NT-proBNP (pg/mL)† | 53 (26 – 105) |
62 (30 – 120) |
65 (33 – 121) |
69 (36 – 134) |
95 (47 – 179) |
0.0005 |
BMI, body mass index; eGFR, estimated glomerular filtration rate; CRP, C-reactive protein; NT-proBNP, N-terminal pro–B-type natriuretic peptide.
*
Values are mean (standard deviation) for continuous variables and percentages for categorical variables unless otherwise specified.
†
Data are expressed as median (25th – 75th percentile).