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. Author manuscript; available in PMC: 2017 Sep 5.
Published in final edited form as: Gene Expr. 2015;16(4):187–196. doi: 10.3727/105221615X14399878166230

Figure 6.

Figure 6

GCN5 suppression inhibits human colon cancer cell growth. (A, B) HCT116 or HT9 colon cancer cells were treated with GCN5 inhibitor at each indicated concentration. The histone H3 acetylation at the lysine residue 9 (H3K9) was determined by Western blotting (B). The growth of treated cells in (A) was analyzed. Error bars represent data from three independent experiments (mean + SD). (C) The percentage of apoptotic cells in (B) was analyzed by annexin V staining and flow cytometry. Data are representative from three independent experiments (mean ± SD). Student’s t-test was used for the statistic analysis. *p < 0.05 and **p < 0.01. (D) A proposed model of GCN5 in colon cancer cell growth.