Figure 6. Gene expression analysis of macrophage depleted hearts post cryo-injury identifies molecular targets regulating ECM regulation during regeneration.
RT-PCR analysis of 7dpi cryo-injured hearts isolated from Clo-Lipo and PBS-Lipo control animals. Heart ventricle samples were screened for a list of candidate genes (partially isolated from previous RNAseq studies) that regulate ECM turnover and maturation during regeneration. N=5 animals, at least 3 independent experiments performed. (see methods section for statistics).