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. Author manuscript; available in PMC: 2017 Sep 19.
Published in final edited form as: NPJ Vaccines. 2017 Apr 10;2:10. doi: 10.1038/s41541-017-0011-y

Figure 1. IgG titers against the N-terminal region, repeat region and C-terminal region of P. falciparum CSP.

Figure 1

Mice immunized 2 or 3 times (n=12 per group) with Pf rCSP-CAF09 developed comparable antibody titers against the P. falciparum CSP N-terminal peptide (A) and the repeat region peptide (B). However, 3 immunizations resulted in significantly higher titers against the C-terminal region (C). Titers are reported as the corresponding sera dilution at which OD405 was 1.0. Horizontal lines represent the geometric mean titer of the group. Abbreviations: ns, not significant; Pf rCSP, P. falciparum recombinant circumsporozoite protein; OD, optical density.