Table 1.

Intrauterine survival of Meox2Cre-Thbd-null mice

Mating: male Meox2Cre-Thbd+/− × female ThbdloxP/loxP
Offspring genotype	Male	Female	Total
E 15–18	–	–
ThbdloxP/lacZ Meox2Cre	–	–	14
Thbd+/lacZ Meox2Cre	–	–	11
ThbdloxP/lacZ	–	–	11
Thbd+/lox	–	–	7
3 weeks
ThbdloxP/lacZ Meox2Cre	13	8	21*
Thbd+/lacZ Meox2Cre	28	31	59
ThbdloxP/lacZ	33	34	67
Thbd+/lox	33	28	61

Genotype frequencies at 15 to 18 days postcoitum and at 3 weeks postpartum, statistically tested against expected frequencies. Findings indicate selective loss of Meox2Cre-Thbd-null mice between the 2 time points.

−, allele deleted; +, wild-type allele; E, embryonic day; lox, loxP-flanked gene.

^*P < .05 (χ² analysis).