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. Author manuscript; available in PMC: 2018 Oct 3.
Published in final edited form as: JBMR Plus. 2017 Nov 21;2(1):32–47. doi: 10.1002/jbm4.10023

Fig. 2.

Fig. 2

Identification of potential Fgf23 enhancers and production of Fgf23−16KO mice. (A) ChIP-seq tag density (normalized to 107 tags) for histone modifications and CTCF binding across the Fgf23 gene locus in differentiated IDG-SW3 osteocytes. (B) Schematic describing the deletion of the −16kb region from the mouse genome via CRSIPR-Cas9 genome editing.