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. Author manuscript; available in PMC: 2019 Apr 10.
Published in final edited form as: AJNR Am J Neuroradiol. 2018 Jan 25;39(3):507–514. doi: 10.3174/ajnr.A5526

Figure 1. Individual biopsies from areas of intact and disrupted vascular function exhibit distinct histopathologic characteristics.

Figure 1

Panel A shows biopsy locations overlaid onto T1 post-contrast, FLAIR, and BOLD images with correlative histopathology in panels B and C. The sample from relatively normal BOLD signal, representing normal vascular function (orange, Panel B), shows normal cellularity and high NeuN staining, suggestive of non-infiltrated gray matter, whereas the sample from a region of BOLD signal abnormality (green, Panel C) shows tumor tissue and no neuronal staining.