Table 2.
Comparison of Clinical Characteristics of 375 Hospitalized Community-Acquired Pneumonia Patients Aged <10 Years With and Without Rhinovirus Viremia
| Characteristic | RV viremia | ||
|---|---|---|---|
| Positive, no. (%) | Negative, no. (%) | P value | |
| Total | 57 (15.2) | 318 (84.8) | |
| Female sex | 28 (49.1) | 139 (43.7) | NS |
| Age, y, median (IQR) | 2.0 (1–4) | 2.0 (0–5) | NS |
| Symptoms at presentation | |||
| Cough | 52 (91.2) | 292 (91.8) | NS |
| Wheezing | 49 (86.0) | 195 (61.3) | <.05 |
| Shortness of breath | 47 (82.5) | 222 (69.8) | NS |
| Fever/feverish | 42 (73.7) | 256 (80.5) | NS |
| Rhinorrhea | 42 (73.7) | 234 (73.6) | NS |
| Anorexia | 38 (66.7) | 224 (70.4) | NS |
| Chest retractions | 35 (61.4) | 146 (45.9) | <.05 |
| Patient interview | |||
| Respiratory illness in the past month | 16 (28.1) | 80 (25.2) | NS |
| Ever diagnosed with pneumonia | 16 (28.1) | 69 (21.7) | NS |
| Antibiotics prior to hospitalization | 7 (12.3) | 58 (18.2) | NS |
| Supplemental oxygen at home | 3 (5.3) | 12 (3.8) | NS |
| Influenza antivirals prior to hospitalization | 0 (0.0) | 4 (1.3) | NS |
| Social history | |||
| Lives in household with indoor or outdoor smoking | 23 (40.4) | 119 (37.4) | NS |
| Household member with respiratory illness in past month | 21 (36.8) | 107 (33.7) | NS |
| Attend daycare (among persons aged <6 y) | 14/50 (28.0) | 72/260 (27.7) | NS |
| Medical conditions | |||
| Any 1 condition | 42 (73.7) | 174 (54.7) | <.05 |
| Asthma/reactive airway disease | 34 (59.7) | 131 (41.2) | <.05 |
| Congenital heart disease | 6 (10.5) | 17 (5.4) | NS |
| Neurologic disorder | 6 (10.5) | 17 (5.4) | NS |
| Preterm birth among persons aged <2 y | 7/28 (25) | 30/158 (19) | NS |
| Hospitalization | |||
| Intensive care unit admission | 13 (22.8) | 70 (22.0) | NS |
| Mechanical ventilation | 4 (7.0) | 21 (6.6) | NS |
| Death | 0 (0.0) | 1 (0.3) | NS |
| Hospital stay, d, median (IQR) | 2/1–3 | 2/1–4 | NS |
| Chest radiograph features (within 48 h of admission)a | |||
| Alveolar and/or interstitial infiltrate | 28 (50.0) | 156 (52.7) | NS |
| Consolidation | 26 (46.4) | 138 (46.6) | NS |
| Complicated bronchiolitis | 22 (39.3) | 114 (38.5) | NS |
| Pleural effusion | 0 (0.0) | 28 (9.5) | NS |
Abbreviations; IQR, interquartile range; NS, not significant; RV, rhinovirus.
a
Among patients with an abnormal initial chest radiograph