Table 2. Biological processes and molecular function enrichment in TT genes closer than 10 Kb.
Biological processes and molecular functions enriched in the 3,734 genes forming TT pairs closer than 10 Kb, a size range significantly enriched in TT gene pairs. Methods and column labels are like in Table 1.
| Biological Process | observed | expected | P value |
|---|---|---|---|
| Protein modification | 236 | 167.74 | 2.87E-05 |
| Protein metabolism and modification | 536 | 440.74 | 4.44E-05 |
| Chromatin packaging and remodeling | 64 | 34.36 | 5.13E-04 |
| Cell structure and motility | 221 | 166.44 | 6.28E-04 |
| DNA repair | 48 | 24.5 | 3.19E-03 |
| Nucleoside, nucleotide and nucleic acid metabolism | 561 | 484.67 | 4.48E-03 |
| Intracellular protein traffic | 189 | 146.14 | 9.02E-03 |
| Protein phosphorylation | 134 | 95.69 | 2.01E-02 |
| Molecular Function | observed | expected | P value |
| Select regulatory molecule | 248 | 172.53 | 5.07E-07 |
| Hydrolase | 166 | 106.71 | 1.16E-06 |
| Kinase | 155 | 99.17 | 2.46E-06 |
| Transferase | 180 | 128.16 | 1.78E-04 |
| Nucleic acid binding | 491 | 413.19 | 1.18E-03 |
| Other enzyme regulator | 27 | 10.44 | 2.10E-03 |
| Transporter | 129 | 93.95 | 8.47E-03 |
| Protein kinase | 112 | 76.69 | 1.25E-02 |
| Histone | 28 | 12.47 | 1.63E-02 |
| Non-receptor serine/threonine protein kinase | 71 | 43.93 | 1.91E-02 |