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. Author manuscript; available in PMC: 2009 Aug 4.
Published in final edited form as: J Neurosci. 2009 Feb 4;29(5):1469–1479. doi: 10.1523/JNEUROSCI.4240-08.2009

Figure 3.

Figure 3

CPPG-evoked ON EPSCs and KA-evoked OFF EPSCs recorded from ON-OFF RGCs. A and B, CPPG-evoked (A) and KA-evoked (B) EPSCs (Vhold = +40 mV) recorded from the same cell in the absence and presence of the NR2B NMDAR antagonist Ro 25-6981 (3 μM). C, correlation between the fraction of ON and OFF QEPSC remaining in the presence of Ro 25-6981. Closed marker represents average ± SD (n=6); open markers represent data from individual cells. Dashed line indicates equal inhibition of ON and OFF EPSCs. Ro25-6981 reduced the ON component of the EPSCs more than the OFF component (p= 0.004, paired t test).