. Author manuscript; available in PMC: 2018 Jun 28.

Published in final edited form as: Curr Dev Nutr. 2017 Sep 6;1(12):cdn.116.000265. doi: 10.3945/cdn.116.000265

Table 1.

Plasma fractional transfer coefficients in control, VA-, and VARA-supplemented neonatal rats dosed orally with [³H]retinol on postnatal day 4¹

Parameter	L(I,J) ± SEM
Parameter	Control	VA	VARA
Transit of retinol through digestive system	26.9 ± 2.0^a	31.9 ± 13.4^ab	11.5 ± 1.2^b
Uptake of CM-REs from plasma to organs	567 ± 95.2	508 ± 135	647 ± 105
Release of RBP-ROH from liver to plasma	2.5 ± 0.1^a	4.0 ± 0.2^b	5.5 ± 0.1^c
Uptake of RBP-ROH from plasma to organs	29.8 ± 0.8^a	245 ± 184^ab	169.4 ± 3.2^b
Recycling of RBP-ROH from organs to plasma	0.3 ± 0.0^a	1.2 ± 0.1^b	0.8 ± 0.0^c
Irreversible loss of retinol from organs	0.06 ± 0.00^a	0.01 ± 0.01^b	0.01 ± 0.00^b

CM-REs, chylomicron retinyl esters; RBP-ROH, retinol bound to retinol-binding protein; VA, vitamin A; VARA, vitamin A combined with retinoic acid.

^a,b,c

Mean values within a row with unlike superscript letters are significantly different (P < 0.05; ANOVA).