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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Hum Brain Mapp. 2018 Feb 9;39(5):2246–2257. doi: 10.1002/hbm.24003

Table IV.

Regression results using connectivity for seeds ROIs and depression group

Seed ROI Cluster location MNI coordinates (x, y, z) Cluster size (voxels) t-value Average connectivitya NoDep (n = 28) Average connectivity PastDep (n = 13) Average connectivity CurrentDep (n = 33)
pgACC R. postcentral gyrus extending to SMAb 14, −50, 65 1,065 4.92 0.09 (1.9) 0.58 (2.5) 2.76 (2.3)*
L. middle frontal gyrus extending to dlPFCb −53, 22, 34 469 4.82 −0.76 (2.2) −0.27 (2.8) 2.18 (2.8)*
R. postcentral gyrus 66, −20, 41 443 4.60 0.10 (2.2) −0.68 (2.9) 2.86 (2.5)*
L. superior temporal gyrus (BA 22) −61, −6, 0 153 4.77 0.60 (3.1) 0.90 (3.3) 3.89 (3.1)*

All regression results were significant after controlling for age (pFWE = 0.05, uncorrected p = 0.001).

a

Average connectivity scores correspond to z-scores; means and standard deviations are reported for each depression group.

b

SMA = supplementary motor area, dlPFC = dorsolateral prefrontal cortex.

*

The CurrentDep group had significantly greater connectivity than both the PastDep and NoDep groups (each p < 0.05).