Table 2.
Genotype | ||||||
---|---|---|---|---|---|---|
N | C/C | C/T | T/T | χ2 (1 d.f.) | p-value | |
CASES—from linked families a | 26 | 21 | 2 | 3 | 6.10 | 0.014 |
CASES—from unlinked families a | 82 | 71 | 9 | 2 | 0.91 | 0.341 |
CASES---TOTAL | 108 | 92 | 11 | 5 | 2.84 | 0.090 |
CONTROLS—TOTAL | 113 | 102 | 9 | 2 | -- | -- |
Cases are from multiplex CL/P families from Shanghai, China. “Linked families” are families with evidence of linkage to anonymous STRP marker D4S1629 in 4q31-q32, HLODMAX is 158 Mb from 4pter.9