Table V.
Stratified atrophy measures
| Raw hippocampal atrophy (per year) | ||||
| Strata | Traced | FS 6.0.0 | sf+ | FS 5.3.0 |
|
| ||||
| All (n=664) | −19.81 mm3 (−0.31%) | −31.93 mm3 (−0.41%) | −32.62 mm3 (−0.49%) | −42.57 mm3 (−0.54%) |
| <55 (n=171) | +16.65 mm3 (+0.26%) | −5.37 mm3 (−0.07%) | +0.18 mm3 (0.00%) | −12.97 mm3 (−0.16%) |
| 55–70 (n=364) | −22.42 mm3 (−0.34%) | −34.05 mm3 (−0.43%) | −32.38 mm3 (−0.47%) | −39.27 mm3 (−0.49%) |
| >70 (n=129) | −61.84 mm3 (−1.05%) | −59.68 mm3 (−0.83%) | −61.83 mm3 (−1.00%) | −76.85 mm3 (−1.07%) |
|
| ||||
| TIV-adjusted hippocampal atrophy (per year) | ||||
| Strata | Traced | FS 6.0.0 | sf+ | FS 5.3.0 |
|
| ||||
| All (n=664) | −19.49 mm3 (−0.30%) | −33.91 mm3 (−0.44%) | −34.37 mm3 (−0.51%) | −44.19 mm3 (−0.55%) |
| <55 (n=171) | +15.73 mm3 (+0.25%) | −4.68 mm3 (−0.04%) | +0.79 mm3 (+0.03%) | −12.54 mm3 (−0.14%) |
| 55–70 (n=364) | −26.53 mm3 (−0.39%) | −44.18 mm3 (−0.55%) | −41.3 mm3 (−0.59%) | −49.03 mm3 (−0.60%) |
| >70 (n=129) | −61.56 mm3 (−1.05%) | −57.78 mm3 (−0.81%) | −60.16 mm3 (−0.98%) | −76.41 mm3 (−1.07%) |
Regression coefficients for each age stratum and method, expressed as mm3, calculated by linear glm, and plotted in Fig 5. The same data are also expressed as a percentage of existing volume lost each year, calculated with a gamma family log-link glm, and plotted in Fig 6. glm = generalized linear model