Figure 3. Effectiveness of (+) JQ1 on inhibiting BRD4 binding.
A) Elution pattern of BRD4 in the presence of 1 μM (+) JQ1 compared to DMSO control in OVCA429 cells. B) Elution profile of ARID1a in the presence of 1 μM (+) JQ1 compared to DMSO control in OVCA429 cells. Band intensity is indicated for 0 mM- 500 mM fraction with DMSO or (+) JQ1. Please click here to view a larger version of this figure.