Table 1.
Univariate Risk Factor Analysisa
| Variable | Proportion With Sz (95% CI) | No. (%) of Patients With Finding | OR (95% CI) | P Valueb |
|---|---|---|---|---|
| PDR | 0.10 (0.08–0.12) | 1166 (21.5) | 0.711 (0.50–0.92) | <.001 |
| BRDs | 0.69 (0.62–0.76) | 176 (3.2) | 18.805 (18.47–19.14) | <.001 |
| Unreactive background | 0.18 (0.15–0.22) | 454 (8.4) | 1.610 (1.36–1.86) | <.001 |
| Prior Sz | 0.23 (0.20–0.25) | 1168 (21.5) | 2.663 (2.50–2.83) | <.001 |
| GRDA | 0.13 (0.11–0.15) | 927 (17.1) | 1.071 (0.862–1.28) | .51 |
| LRDA | 0.28 (0.23–0.32) | 410 (7.6) | 2.967 (2.73–3.20) | <.001 |
| GPDs | 0.16 (0.13–19) | 696 (12.8) | 1.368 (1.15–1.59) | <.01 |
| LPDs | 0.44 (0.41–0.48) | 802 (14.8) | 9.825 (9.65–10.0) | <.001 |
| BIPDs | 0.28 (0.21–0.36) | 122 (2.2) | 2.784 (2.38–3.19) | <.001 |
| Infection | 0.16 (0.11–0.24) | 118 (2.2) | 1.350 (0.853–1.85) | .26 |
| Inflammation | 0.13 (0.06–0.24) | 56 (1.0) | 0.998 (0.202–1.80) | .99 |
| Neoplasm | 0.19 (0.16–0.22) | 577 (10.6) | 1.694 (1.47–1.92) | <.001 |
| ICH | 0.12 (0.10–0.15) | 543 (10.0) | 0.963 (0.693–1.23) | .84 |
| Metabolic encephalopathy | 0.06 (0.04–0.10) | 325 (6.0) | 0.467 (0.0177–0.916) | <.001 |
| Stroke | 0.10 (0.07–0.13) | 452 (8.3) | 0.737 (0.416–1.059) | .06 |
| SAH | 0.07 (0.05–0.09) | 508 (9.4) | 0.499 (0.140–0.845) | <.001 |
| SDH | 0.13 (0.10–0.17) | 353 (6.5) | 1.078 (0.760–1.40) | .62 |
| TBI | 0.07 (0.04–0.12) | 142 (2.6) | 0.523 (0–1.170) | .05 |
| Hypoxic/ischemic | 0.13 (0.10–0.16) | 390 (7.2) | 1.004 (0.694–1.311) | .99 |
| IVH | 0.10 (0.06–015) | 146 (2.7) | 0.736 (0.180–1.29) | .31 |
| Hydrocephalus | 0.07 (0.03–0.14) | 86 (1.6) | 0.520 (0–1.35) | .14 |
| Discharges | 0.29 (0.26–0.33) | 763 (14.1) | 3.733 (3.55–3.91) | <.001 |
| Frequency (>2Hz)c | 0.42 (0.32–53) | 77 (1.4) | 2.570 (1.62–4.09) | <.001 |
Abbreviations: BIPD, bilateral periodic discharges; BRDs, brief rhythmic discharges; GPDs, generalized periodic discharges; GRDA, generalized rhythmic delta activity; ICH, intracranial hemorrhage; IVH, intraventricular hemorrhage; LPDs, lateralized periodic discharges; LRDA, lateralized rhythmic delta activity; OR, odds ratio; PDR, posterior dominant rhythm; Prop, proportion with seizures; SAH, subarachnoid hemorrhage; SDH, subdural hemorrhage; Sz, seizure; TBI, traumatic brain injury.
a
A total of 2868 were men (49.9%), median age; 61 years.
b
P value calculated with Fisher exact test.
c
Variable only evaluated for ictal-interical continuum patterns.