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Excitatory synaptic bursts are induced by controlled cortical impact (CCI). (A) Voltage-clamp recording of spontaneous excitatory burst discharge observed in a CCI animal with an epileptiform EEG. Note the burst is comprised of compound sEPSCs and resembles paroxysmal discharges observed in epileptic animals. (B) Bar charts of average values of various burst properties for control (n = 20) or CCI (n = 32). *P < 0.05, **P < 0.01.
