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. Author manuscript; available in PMC: 2018 Dec 26.
Published in final edited form as: Int J Gynecol Pathol. 2019 Jan;38(Suppl 1):S64–S74. doi: 10.1097/PGP.0000000000000518

Figure 3. The Cancer Genome Atlas (TCGA) mutational data arranged by genomic clusters.

Figure 3

Data from TCGA showing that TP53 mutation analysis is a sensitive and specific method for distinguishing between copy number high and copy number low tumors. Note however that TP53 mutations are also seen in POLE and microsatellite instability-high (MSI-H) tumors.