Table 2.
Crude and adjusted differences in language and cognitive test scores between unexposed children and children in each exposure group.
| Crude and adjusted differences in neuropsychological test scores in children in each exposure duration quartile compared with unexposed children | ||||
|---|---|---|---|---|
| n | Crude, difference (95% CI) | Adjusted for patient characteristics Adjusted difference* (95% CI) |
Adjusted for patient characteristics and RUB Adjusted difference** (95% CI) |
|
| CELF Receptive | ||||
| Unexposed | 1378 | Reference | Reference | Reference |
| First Quartile (≤25 min) | 36 | 0.7 (−4.7 – 6) | 0 (−5.2 – 5.1) | 0.1 (−5.1 – 5.2) |
| Second Quartile (>25 to ≤ 35 min) | 43 | −3.4 (−8.3 – 1.5) | −2.8 (−7.5 – 1.8) | −2.7 (−7.4 – 2) |
| Third Quartile (>35 to ≤ 60 min) | 38 | −4.3 (−9.5 – 0.9) | −4.8 (−9.9 – 0.2) | −4.1 (−9.3 – 1.1) |
| Fourth Quartile (>60 min) | 31 | −7.8 (−13.6 – −2.1) | −6.6 (−12.1 – −1.1) | −5.6 (−11.3 – 0.05) |
| No Record | 96 | 4.5 (−7.8 – −1.1) | −3.9 (−7.2 – −0.6) | −3.7 (−7 – −0.4) |
| CELF Expressive | ||||
| Unexposed | 1378 | Reference | Reference | Reference |
| First Quartile (≤25 min) | 36 | 1.7 (−3.3 – 6.8) | 1 (−3.9 – 5.9) | 1 (−3.9 – 5.9) |
| Second Quartile (>25 to ≤ 35 min) | 43 | −1.3 (−5.9 – 3.4) | −1 (−5.4 – 3.4) | −1 (−5.4 – 3.5) |
| Third Quartile (>35 to ≤ 60 min) | 38 | −5.9 (−10.8 – −1) | −6.6 (−11.4 – −1.8) | −6.1 (−11 – −1.2) |
| Fourth Quartile (>60 min) | 31 | −8.3 (−13.7 – −2.9) | −7.1 (−12.3 – −1.9) | −6.3 (−11.6 – −0.9) |
| No Record | 96 | −4.8 (−7.9 – −1.6) | −4.3 (−7.5 – −1.2) | 4.3 (−7.5 – −1.2) |
| CELF Total | ||||
| Unexposed | 1378 | Reference | Reference | Reference |
| First Quartile (≤25 min) | 36 | 1.4 (−3.7 – 6.5) | 0.7 (−4.2 – 5.6) | 0.7 (−4.2 – 5.6) |
| Second Quartile (>25 to ≤ 35 min) | 43 | −2.4 (−7.1 – 2.2) | −2 (−6.4 – 2.5) | −1.9 (−6.3 – 2.6) |
| Third Quartile (>35 to ≤ 60 min) | 38 | −5.3 (−10.3 – −0.4) | −5.9 (−10.7 – −1.2) | −5.3 (−10.2 –− 0.4) |
| Fourth Quartile (>60 min) | 31 | −8.5 (−13.9 – −3) | −7.2 (−12.4 – −2) | −6.2 (−11.6 – −0.9) |
| No Record | 96 | 4.8 (−8 – −1.6) | −4.3 (−7.4 – −1.1) | 4.2 (−7.3 – −1) |
| CPM Total | ||||
| Unexposed | 1378 | Reference | Reference | Reference |
| First Quartile (≤25min) | 36 | −0.2 (−1.4 – 1) | −0.4 (−1.6 – 0.8) | −0.4 (−1.6 – 0.8) |
| Second Quartile (>25 to ≤ 35 min) | 43 | −0.7 (−1.8 – 0.4) | −0.8 (−1.9 – 0.3) | −0.7 (−1.8 – 0.4) |
| Third Quartile (>35 to ≤ 60 min) | 38 | −0.9 (−2.1 – 0.3) | −1.1 (−2.3 – 0.1) | −0.9 (− −2.1 – 0.3) |
| Fourth Quartile (>60 min) | 31 | −1.7 (−3 – −0.4) | −1.5 (−2.7 – −0.2) | −1.3 (−2.6 – 0.1) |
| No Record | 96 | −1 (−1.7 – −0.2) | −0.9 (−1.7 – −0.2) | −0.9 (−1.7 – −0.1) |
*
Adjusted for sex, race, birthweight (<2500g), maternal school level and income.
**
Adjusted for the above patient characteristics and comorbidity measured by resource utilization band (RUB)