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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Wiley Interdiscip Rev Syst Biol Med. 2018 Feb 23;10(4):e1417. doi: 10.1002/wsbm.1417

Figure 4.

Figure 4

A small section of the drug labels available on PharmGKB. PharmGKB tags FDA labels with a B inside a blue square if the label came from the FDA’s Biomarker list (https://www.fda.gov/drugs/scienceresearch/researchareas/pharmacogenetics/ucm083378.htm). A small set of labels contain specific dosing guidance based on genetic information; these labels are tagged as including dosing information. For example, in the above image, aripiprazole is tagged in this manner because the FDA label states that CYP2D6 poor metabolizers should have their dose reduced by 50%.