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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: J Innate Immun. 2018 Jun 1;10(4):264–278. doi: 10.1159/000489020

FIGURE 1. Outline of the study design and setup for investigating the interaction of P. gingivalis with human dental follicle stem cells and the resulting effects on neutrophils in a newly established triple-culture system.

FIGURE 1

(A) Direct interaction of neutrophils and stem cells. (B) Direct interaction of living P. gingivalis and hDFSCs (Box 1) is required for downstream effects on neutrophils (Box 2). The question is which factors in Box 1 are essential to modify the interaction in Box 2.