Table 1.
Screening strategies evaluated by the microsimulation model
| Screening Modality | Age to Start Screening (years) | Age to Stop Screening (years) | Screening Interval (years) | No. Of (Unique) Strategies a |
|---|---|---|---|---|
| No screening | 1 (1) | |||
| Colonoscopy | 40,45,50 | 75,80,85 | 5,10,15 | 27 (20) |
| Stool-based tests | ||||
| • Fecal immunochemical test | 40,45,50 | 75,80,85 | 1,2,3 | 27 (27) |
| • High-sensitivity guaiac-based fecal occult blood test | 40,45,50 | 75,80,85 | 1,2,3 | 27 (27) |
| • Multitarget stool DNA test | 40,45,50 | 75,80,85 | 1,3,5 | 27 (27) |
| Flexible sigmoidoscopy | 40,45,50 | 75,80,85 | 5,10 | 18 (15) |
| Computed tomographic colonography | 40,45,50 | 75,80,85 | 5,10 | 18 (15) |
| Total | 145 (132) |
a
The number of unique strategies excluded the strategies that overlap (eg, COL every 10 years from ages 50-80 years and from ages 50-85 years both include colonoscopies at age 50, 60, 70, and 80 years, and thus are not unique strategies).