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. Author manuscript; available in PMC: 2019 May 2.
Published in final edited form as: Cold Spring Harb Perspect Med. 2018 Jan 2;8(1):a029868. doi: 10.1101/cshperspect.a029868

Figure 2.

Figure 2

Visualization of possible changes in entropy (dS) across time from the big bang (lowest entropy) to equilibrium (highest entropy). dS = deS = diS, where deS is the flow of entropy caused by exchanges with the surroundings (environment), and diS is the entropy production as a result of processes inside the system, such as diffusion, chemical reactions, and heat conduction (internal metabolism) (Prigogine 1978).