Table 2.

GO categories that were overrepresented among the significantly differentially expressed genes between HCRs and LCRs by functional clustering with DAVID

Category	↑	↓
Mitochondriona	7
Carboxyl acid metabolisma	9
Lipid and lipoprotein metabolisma	7
Lipid catabolisma		3
Oxidoreductase activitya	7
Immune responsea	8
Protein metabolismb		16
Attachment of cytoskeleton proteinsa		6

Data from Kivela et al. 2010, with permission, from the Federation of American Societies for Experimental Biology © 2010.

Values indicate number of genes.

GO, Gene Ontology; HCRs, high-capacity runners; LCRs, low-capacity runners; ↑, gene expression higher in HCRs than in LCRs; ↓, gene expression lower in HCRs than in LCRs.

^aFalse discovery rate (FDR) P < 0.01.

^bFDR P < 0.05.