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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2018 Apr 12;24(8):1759–1765. doi: 10.1016/j.bbmt.2018.03.031

Table 1A.

Characteristics and outcomes of 2 patients with sickle cell disease that underwent HSCT from a haploidentical, related donor with the alemtuzumab, TBI, and PTCy.

Transplantation Characteristics Transplantation Outcomes Transplant-Related Toxicity
No. Age at HSCT (years) Sex Hemoglobin Genotype Indications* Prior Therapy Donor CD34+ Dose (×106/kg) Duration Follow-up (months) Living Status Neutrophil Engraftment Infectious Complications CMV Reactivation aGVHD cGVHD
A 24 F SS 20 VOC/year
3 ACS/lifetime
Hydroxyurea Mother (Hb AS) 5.9 37 Alive Autologous, Day +39 None None None None
B 52 M SC 10 VOC/year Hydroxyurea Sister (Hb AA) 5.4 36 Alive Autologous, Day +34 None Day +11 None None