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. Author manuscript; available in PMC: 2019 Apr 25.
Published in final edited form as: Cochrane Database Syst Rev. 2018 Apr 25;4:CD007105. doi: 10.1002/14651858.CD007105.pub3

Characteristics of studies awaiting assessment [ordered by study ID]

Capdevila 2017
Methods Not yet assessed
Participants Not yet assessed
Interventions Not yet assessed
Outcomes Not yet assessed
Notes Found during top-up search December 2017
Choi 2017
Methods Not yet assessed
Participants Not yet assessed
Interventions Not yet assessed
Outcomes Not yet assessed
Notes Found during top-up search December 2017
Elkaradawy 2012
Methods Not yet assessed
Participants Not yet assessed
Interventions Not yet assessed
Outcomes Not yet assessed
Notes Found during top-up search December 2017
Fiorelli 2016
Methods Not yet assessed
Participants Not yet assessed
Interventions Not yet assessed
Outcomes Not yet assessed
Notes Found during top-up search December 2017
Iohom 2006
Methods Not yet assessed
Participants Not yet assessed
Interventions Not yet assessed
Outcomes Not yet assessed
Notes Found during top-up search December 2017
Jendoubi 2017
Methods Not yet assessed
Participants Not yet assessed
Interventions Not yet assessed
Outcomes Not yet assessed
Notes Found during top-up search December 2017
Kendall 2018
Methods Not yet assessed
Participants Not yet assessed
Interventions Not yet assessed
Outcomes Not yet assessed
Notes Found during top-up search December 2017
Kim 2017
Methods Not yet assessed
Participants Not yet assessed
Interventions Not yet assessed
Outcomes Not yet assessed
Notes Found during top-up search December 2017
Oh 2017
Methods Not yet assessed
Participants Not yet assessed
Interventions Not yet assessed
Outcomes Not yet assessed
Notes Found during top-up search December 2017
Okur 2017
Methods Not yet assessed
Participants Not yet assessed
Interventions Not yet assessed
Outcomes Not yet assessed
Notes Found during top-up search December 2017
Reuben 2006
Methods Double-blinded (patient and outcome assessor), placebo-controlled, RCT
Sequence generation randomized
follow-up: 12 months
Participants Participants: 80 adults, at a teaching hospital, Springfield, MA, USA
Operation: lower limb amputation because of ischaemic necrosis, secondary to peripheral vascular disease
2 groups, size: 40/40
Age (group 1, 2): 68 years (SD ± 12), 65 years (SD ± 17)
Men/women (group 1, 2): 23/17, 25/15
Comorbidities (group 1, 2): BKA:AKA ratio 29:11, 26:14
Interventions Group 1 (treatment): GA (fentanyl), intra-op perineural injection of bupivacaine 10 mL 0.25% and clonidine 100 μg, post-op morphine IV and paracetamol (acetaminophen)/oxycodone orally
Group 2 (placebo): GA (fentanyl), intra-op perineural injection of placebo, post-op morphine IV and paracetamol/oxycodone orally
Adjuvants: clonidine perineurally
Immediate post-op pain control: statistically meaningful reduction in analgesic consumption
Outcomes Dichotomous: phantom limb pain and stump pain at 12 months
Continuous: not reported
Secondary: not reported
Notes The sciatic nerve was infiltrated for AKA or the posterior tibial nerve for BKA
We could not make sense of some numbers reported on attrition
As reported 22 January 2009, SS Reuben was accused of publishing fraudulent data. Up to 22 papers have been or will be retracted by the journals in which they have been published (Retraction notice Anesthesia and Analgesia 20 February 2009 (Shafer 2009)). This article appears not to be among the retracted manuscripts. We placed it in the classification pending section on the advice of Cochrane Anaesthesia, Critical and Emergency Care
Zwaans 2017
Methods Not yet assessed
Participants Not yet assessed
Interventions Not yet assessed
Outcomes Not yet assessed
Notes Found during top-up search December 2017

AKA: above-the-knee amputation; BKA: below-the-knee amputation; GA: general anaesthesia