| Study ID | Regional technique |
Timing of intervention |
Adjuvants | Outcomes | Continuous | Follow-up (month) |
|---|---|---|---|---|---|---|
| Breast cancer surgery | ||||||
| Albi-Feldzer 2013 | Wound instillation and intervertebral block | Postincision, single shot vs placebo | None | Pain/no pain | Brief Pain Index | 3, 6 and 12 months |
| Baudry 2008 | Local Infiltration | Single shot, postincision vs control | None | Pain/no pain | McGill results not reported | 18 months |
| Besic 2014 | Local Infiltration | Postincision, continuous post-op vs control | None | Pain/no pain | None | 3 months |
| Fassoulaki 2000 | Topical application | Preincision, continuous post-op vs placebo | Propoxyphene | Pain/no pain | Verbal Intensity Scale | 3 months |
| Fassoulaki 2001 | Brachial plexus block | Postincision, single shot vs placebo | Mexiletine, propoxyphene | Pain/no pain | VAS | 3 months |
| Fassoulaki 2005 | Topical application | Postincision, continuous postop vs control | Gabapentin | Pain/no pain | Analgesic consumption | 6 months |
| Gacio 2016 | Paravertebral block | Single shot, preincision vs control | Parecoxib, fentanyl, morphine, and adrenaline | Pain/no pain | None | 6 months |
| Grigoras 2012 | IV lidocaine | Preincision, continuous intra-op vs placebo | None | Pain/no pain | Short-form McGill Pain Questionnaire | 3 months |
| Ibarra 2011 | Single shot, paravertebral block | Single shot, preincision vs control | None | Myofascial, phantom or neuropathic pain | None | 3 and 5 months |
| Kairaluoma 2006 | Single shot, paravertebral block | Single shot, preincision vs control | None | NRS > 3 | Analgesic consumption | 12 months |
| Karmakar 2014 | Thoracic paravertebral block | Single shot, preincision vs pre incision, continuous vs control | Epinephrine | Pain/no pain | VRS | 3 and 6 months |
| Lam 2015 | Paravertebral block | Not specified | None | Pain/no pain | None | 6 months |
| Lee 2013 | Paravertebral block | Preincision, continuous intra-op and post-op vs control | Pregabalin | Pain/no pain | Short-form McGill Pain Questionnaire | 3 months |
| Micha 2012 | Local infiltration with brachial plexus and interscalene block | Postincision, single shot vs placebo | None | DN4 | None | 6 months |
| Strazisar 2012 | Local infiltration | Postincision, continuous post-op vs control | None | Pain/no pain | None | 3 months |
| Strazisar 2014 | Local infiltration | Postincision, continuous post-op vs control | None | Pain/no pain | None | 3 months |
| Tecirli 2014 | Intercostal nerve block | Postincision, single shot vs control | None | DN4 | VAS | 3 months |
| Terkawi 2015b | IV lidocaine | Preincision, continuous intra-op and post-op vs placebo | None | Pain/no pain | VAS | 6 months |
| Caesarean section | ||||||
| Bollag 2012 | Transversus abdominis plane block | Single shot, post-op vs placebo | Clonidine | None | Short form McGill Pain Questionnaire | 3, 6 and 12 months |
| Lavand’homme 2007 | Wound irrigation | Preincision, continuous post-op vs control | None | Pain/no pain | Analgesic consumption | 6 months |
| Loane 2012 | Transversus abdominis plane block | Postincision, single shot vs placebo | None | Pain/no pain | None | 3 months |
| McKeen 2014 | Transversus abdominis plane block | Postincision, single shot vs placebo | None | None | SF-36 | 6 months |
| Shahin 2010 | Peritoneal instillation | Postincision, single shot vs placebo | None | Pain/no pain | NRS | 8 months |
| Singh 2013 | Transversus abdominis plane block | Postincision, single shot vs placebo | None | None | NRS | 3 months |
| Iliac crest bone graft | ||||||
| Barkhuysen 2010 | Local infiltration | Postincision, single shot vs control | Epinephrine | Pain/no pain | None | 1 Year |
| Gundes 2000 | Wound instillation | Postincision, single shot vs placebo | None | Pain and dysaesthesia vs none | None | 3 months |
| Singh 2007 | Wound irrigation | Postincision, continuous post-op vs control | None | Pain/no pain | VAS, pain frequency, functional activity score, overall satisfaction | 4.7 years |
| Prostatectomy | ||||||
| Brown 2004 | Spinal | Preincision, continuous intra-op vs placebo | Clonidine | Pain/no pain | Numerical Pain Scale, SF-36 | 3 months |
| Gupta 2006 | Epidural | Continuos, post-op vs placebo | Adrenaline | None | SF-36 | 3 months |
| Thoracatomy | ||||||
| Can 2013 | Epidural | Single shot, preincision vs preincision, continuous vs control | None | Pain/no pain | VAS, patient satisfaction | 6 months |
| Comez 2015 | Epidural | Preincision, continuous intra-op vs control | Dexketoprofen, morphine, and fentanyl | Pain/no pain | VAS | 3 and 6 months |
| Ju 2008 | Epidural | Preincision and post-op vs control | None | Pain/no pain | Allodynia | 12 months |
| Katz 1996 | Intercostal nerve block | Single shot, postincision vs control | None | Pain/no pain | VRS, analgesic consumption | 18 months |
| Liu 2015 | Wound irrigation | Postincision, continuous post-op vs control | Fentanyl | Pain/no pain | None | 3 months |
| Lu 2008 | Epidural | Preincision vs post-op vs control | None | Pain/no pain | None | 6 months |
| Senturk 2002 | Epidural | Preincision vs post-op vs control | None | Pain/no pain | NRS, pain affecting daily living | 6 months |
| Vaginal hysterectomy | ||||||
| Purwar 2015 | Spinal | Single shot, preincision vs control | Fentanyl | None | VAS, SF-36 | 3 months |
| Sprung 2006 | Spinal | Single shot, preincision vs control | Clonidine | None | NRS, SF-36 | 3 months |
| Abdominal hysterectomy | ||||||
| Wodlin 2011 | Spinal | Single shot, preincision vs control | None | None | SF-36 | 6 months |
DN4: Douleur Neuropathique 4, a pain questionnaire; NRS: numerical rating scale; SF-36: Short Form Health Survey; VAS: visual analogue scale; VRS: verbal rating scale