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. Author manuscript; available in PMC: 2019 Apr 25.
Published in final edited form as: Cochrane Database Syst Rev. 2018 Apr 25;4:CD007105. doi: 10.1002/14651858.CD007105.pub3
Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 PPP three to 18 months after thoracotomy 7 499 Odds Ratio (M-H, Random, 95% CI) 0.52 [0.32, 0.84]
2 PPP three to six months after cardiac surgery 2 116 Mean Difference (IV, Random, 95% CI) −0.76 [−1.73, 0.21]
3 PPP three to twelve months after breast cancer surgery 18 1297 Odds Ratio (M-H, Random, 95% CI) 0.43 [0.28, 0.68]
 3.1 Paravertebral block 6 419 Odds Ratio (M-H, Random, 95% CI) 0.61 [0.39, 0.97]
 3.2 Intravenous lidocaine 2 97 Odds Ratio (M-H, Random, 95% CI) 0.24 [0.08, 0.69]
 3.3 Multimodal block 4 402 Odds Ratio (M-H, Random, 95% CI) 0.76 [0.32, 1.77]
 3.4 Local infiltration 6 379 Odds Ratio (M-H, Random, 95% CI) 0.29 [0.12, 0.73]
4 PPP three to eight months after caesarean section 4 551 Odds Ratio (M-H, Random, 95% CI) 0.46 [0.28, 0.78]
5 Pain score three to six months after caesarean section 2 110 Std. Mean Difference (IV, Random, 95% CI) 0.14 [−0.34, 0.61]
6 PPP three to 55 months after Iliac crest bone graft 3 123 Odds Ratio (M-H, Random, 95% CI) 0.20 [0.04, 1.09]
7 PPP six to 12 months after amputation 2 108 Odds Ratio (M-H, Random, 95% CI) 0.53 [0.21, 1.33]
8 PPP six to 12 months after laparotomy 2 Odds Ratio (M-H, Random, 95% CI) Totals not selected
9 PPP three to 12 months after hernia repair 2 Odds Ratio (M-H, Random, 95% CI) Totals not selected
10 Pain score three months after prostatectomy 2 150 Std. Mean Difference (IV, Random, 95% CI) 0.06 [−0.26, 0.38]
11 SF-36 bodily pain score at three to six months after hysterectomy 3 297 Mean Difference (IV, Random, 95% CI) 1.70 [−1.06, 4.46]