Table 3. Inflammatory Markers Before and After Smoking Cessation.

Baseline inflammatory marker levels and the mean percent changes in inflammatory markers between each study visit 2–4 (V2–V4) vs. baseline (V1) are shown with the level of significance.

Marker	Baseline value (mean±SD)	Visit	Mean % change from baseline (95% CI)	Significance
TNF	1.213 (0.703) pg/ml	V1	0
		V2	−14.5 (−49.8, 45.5)
		V3	−27.7 (−57.6, 23.0)	vs. V2, P<0.0115
		V4	−20.2 (−53.1, 35.9)
sTNFRI	2667.9 (1066.4) pg/ml	V1	0	vs. V4, P<0.0001
		V2	−3.0 (−7.9, 2.2)	vs. V4, P<0.01
		V3	−3.9 (−8.7, 1.2)	vs. V4, P<0.0068
		V4	−11.6 (−16.1, −7.0)
sTNFRII	2395.1 (993.1) pg/ml	V1	0	vs. V4, P<0.0048
		V2	−10.4 (−18.9, −1.0)	vs. V4, N.S.
		V3	−3.2 (−12.3, 6.9)	vs. V4, P<0.0021
		V4	−13.7 (−21.8, −4.7)
sVCAM-1	310.1 (119.3) ng/ml	V1	0	vs. V4, P<0.0001
		V2	−0.6 (−8.8, 8.3)	vs. V4, P<0.0001
		V3	−4.1 (−11.9, 4.4)	vs. V4, P<0.0001
		V4	−19.5 (−26.0, −12.3)
IL-6*	3.314 (2.873) pg/ml	V1	0	N.S.
		V2	15.0 (−10.8, 48.4)
		V3	0.7 (−21.8, 29.7)
		V4	−9.6 (−29.8, 16.4)
CRP*	0.462 (0.519) mg/dL	V1	0	N.S.
		V2	−46.5 (−75.7, 18.0)
		V3	−54.4 (−79.1, −0.3)
		V4	−19.1 (−63.0, 76.8)

^*Pairwise comparisons of visits 2 through 4 were not carried out due to non-significant (N.S.) findings.