Table 2.
Multivariate Cox Regression Analysis of Factors Associated with Primary Endpoint (RP+LF) for the 149 Randomized Patients
| Variable | Randomized Patients (n=149) | |
|---|---|---|
| HR (95% CI) | P Value | |
| Time of Enrollment | ||
| Before 9/27/2011 (Ref) | ||
| After 9/27/2011 | 0.35 (0.17–0.72) | 0.004 |
| Performance status | ||
| ≤80 (Ref) | ||
| ≥90 | 1.00 (0.54–1.87) | 0.997 |
| Total RT Dose | ||
| <74 Gy (Ref) | ||
| ≥74 Gy | 0.99 (0.44–2.18) | 0.971 |
| Tumor histology | ||
| Adeno (Ref) | ||
| Not Adeno | 0.99 (0.54–1.79) | 0.963 |
| RT type | ||
| IMRT (Ref) | ||
| Proton | 1.35 (0.73–2.48) | 0.34 |
| Heart mean dose | ||
| Continuous | 1.02 (0.99–1.06) | 0.234 |