. Author manuscript; available in PMC: 2018 Jun 28.

Published in final edited form as: JOR Spine. 2018 May 21;1(2):e1014. doi: 10.1002/jsp2.1014

TABLE 3.

Pain, structural intervertebral disc (IVD) degeneration, and intradiscal pro-inflammatory cytokines correlate

		IVD degeneration	Normalized IVD height	% Intradiscal TNFα positivity	% Intradiscall L-1β positivity
Normalized paw withdrawal threshold	r (P)	−0.694 (<0.001)	0.508 (0.002)	−0.562 (0.001)	−0.452 (0.011)
IVD degeneration	r (P)	1	−0.630 (<0.001)	0.476 (0.004)	0.351 (0.05)
NormalizedIVD height	r (P)		1	−0.407 (0.017)	−0.466 (0.008)
% Intradiscal TNFα positivity	r (P)			1	0.674 (<0.001)

Abbreviations: IL-1β, interleukin-1 beta; TNFα, tumor necrosis factor-alpha. Bold indicates significant correlations.