Table A2.
Characteristic | No. of Patients (%) | P | |
---|---|---|---|
Genomic (n = 22) | Nongenomic (n = 54) | ||
Age, years, median (range) | 58.5 (17–73) | 56 (25–81) | 1.00 |
No. of prior lines of therapy for metastatic disease, mean (range) | 2.2 (0–8) | 1.8 (0–10) | .43 |
Sex | |||
Male | 7 (32) | 34 (37) | .79 |
Female | 15 (68) | 20 (63) | |
No. of alterations, mean (range) | 5.5 (2–10) | 4.4 (1–10) | .08 |
No. of actionable alterations, mean (range) | 2.5 (0–5) | 1.7 (0–6) | .04 |
Tumor type | |||
Breast triple negative | 4 (18) | 13 (24) | .76 |
Breast ER positive/HER2 negative | 4 (18) | 8 (15) | .74 |
Lung adenocarcinoma | 5 (23) | 4 (7) | .11 |
Lung other | 2 (9) | 3 (6) | .62 |
Cholangiocarcinoma | 2 (9) | 2 (4) | .57 |
SCC head and neck | 0 (0) | 6 (11) | .17 |
Salivary gland | 0 (0) | 4 (7) | .32 |
Brain tumor | 1 (5) | 3 (6) | 1.00 |
Endometrial | 0 (0) | 3 (6) | .55 |
NOTE. Continuous data were compared by t test, and categorical data were compared by Fisher’s exact test using GraphPad version 5.0 software.
Abbreviations: ER, estrogen receptor; HER2, human epidermal growth factor receptor 2; SCC, squamous cell carcinoma.